Great Plains Laboratory

Organic Acids TestOrganic Acids Test (OAT)

Lab Phone Number: 800-288-0383

Purpose of Test

The organic acids test provides an in-depth view into the body’s cellular metabolic processes and its efficiency of metabolic function. Organic acids are metabolic intermediates that are produced in pathways of central energy production, detoxification, neurotransmitter breakdown or intestinal microbial activity. Marked accumulation of specific organic acids detected in urine often signals a metabolic inhibition or block. The metabolic block may be due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up or drug effect. Several of the biomarkers are markers of intestinal bacterial or yeast overgrowth.

The organic acids test (OAT) profile provides vital client information from a single urine specimen. It is valuable for determining:

  • Functional vitamin and mineral status
  • Amino acid insufficiencies like carnitine and NAC
  • Oxidative damage and antioxidant need
  • Phase I & Phase II detoxification capacity
  • Functional B-complex vitamin needs
  • Neurotransmitter metabolites
  • Mitochondrial energy production
  • Methylation sufficiency
  • Lipoic acid and CoQ10 status
  • Markers for bacterial and yeast overgrowth
  • Oxalates, fungal and mold

Direct Lab Price: $309 (Please put your credit card number on the requisition. If the price is not on the requisition – please fill in this price). The price is subject to change if you are re-testing in the future. Depending on your insurance company, this may be covered and the and the deposit would be $200. The lab is in network with most insurance companies except for the following: Aetna, Humana, GEHA, Kaiser, Blue Cross Blue Shield, Medicaid, UMR, Avmed, ODS/Moda, United Healthcare of River Valley, Anthem: California, Florida, Iowa, Kansas, South Dakota, and Hawaii.

Here is a brochure overview:


Here’s a list of the most commonly asked questions and instructions regarding this lab test.

What are the collection requirements?

Step 1 –Please write your Name and DOB on a piece of masking tape and use that to label your vial or use a permanent marker.

Step 2 – Limit liquid intake starting at 6pm the night prior to collection. This is to avoid sample dilution. Urine must be yellow in color. If the urine is clear the sample is too diluted. Discard diluted sample, rinse the collection cup with hot water (no soap), air dry, then re-collect.

Step 3 – We recommend freezing your specimen for at least 4-6 hours before shipping the test. 

Step 4 – Place cap vial into ziplock specimen bag along with absorbent pad. Seal the bag. Place the specimen bag with the sample vial into the kit box.

Step 5 – Fill out the Test Requisition Form completely. Be sure to write the date of sample collection in the Patient section of the form. Payment type must be completed with payment included to process sample unless payment was submitted directly through Fortitude Functional Nutrition. Place Test Request Form into the box with the sample and ship to the laboratory. See shipping instructions below.**

**If you cannot ship the specimen on the day of collection please freeze the sample by placing the box containing the sample into the freezer.

How do I ship the sample?

Specimens may be shipped Monday through Thursday. 

Before shipping, be sure that the Yellow cap vial and the Test Request Form are labeled and completely filled out. Be sure to place the sample vial sealed in the ziplock bag and that the Test Request Form are in the Kit box.

Locate the FedEx Clinical Pak mailer. Fill in your name and address on the shipping label attached to the outside of mailer. Place the kit box into FedEx Clinical Pak. Remove strip to reveal sticky film and press both sides of mailer together to seal the pouch.

Call FedEx to schedule a pick-up. Dial 1-800-238-5355. When the automated greeting begins say “Rep”. When asked if you are shipping a package say “Yes”. A live person will then answer to help schedule your pickup. Let them know you are shipping using a Billable Stamp.

Am I responsible for the postage?
Patients don’t have to pay for postage, test kits include a pre-paid envelope if mailed in the U.S.

However, international customers must pay for shipping unless prior contract exists.

Can I drop off test kit at local FedEx office?
Yes, please follow the packing and shipping instructions provided with the test kit.
Do I need to stop taking any of my medications and/or supplements before I collect my urine sample?

No please do not stop any of your medications before collecting your sample. But, stop all your supplements 72 hours prior to collecting your sample.

Do I need to avoid certain foods before I collect my sample?

Yes, please not stop consuming the following foods 72 hours prior to collection: apples, grapes, pears, and cranberries as well as their juices or any food products that contain them.

I sealed bag but forgot to put the paperwork in kit. Can I reopen?
Yes, just tape to reclose.
Can I ship my specimen on Friday?

NO, you must ship your specimen from Monday – Thursday.

My test kit did not have a Test Requisition Form?

Unless you already received the test requisition in your private portal, you should email or call our office (at or 720-580-2078) for a Test Requisition Form.